Mohammad Shabbir Hasan
Ph.D. Student, Computer Science, Virgina Tech
Hello! Welcome to my website. I am Mohammad Shabbir Hasan, a Ph.D. student and Teaching Assistant at the Department of Computer Science at Virginia Tech, USA.
My research interest includes Next Generation Sequencing, Evolutionary Genomics, Bioinformatics, and Computational Biology. Beside these, I have experience of working on Software Engineering and Web Applications research projects.
Currently I am working in the Computational Biology and Bioinformatics Lab at Virginia Tech. I am working with Prof. Liqing Zhang on calling InDels from Next Generation Sequence (NGS) data. Studies showed that Insertion and Deletions(InDels) of base pairs in the DNA sequence of human may cause changes in gene functions which lead to diseases like schizophrenia, autism, mental retardation and cancers. Moreover, indels also change gene expression and can be used as genetic markers in natural populations. Our goal is to develop efficient algorithms to determine the inserted/deleted regions in DNA sequences from NGS data.
Previously I worked with Prof. Zhong-Hui Duan on Investigating gene-gene relations in microarray data using clustering algorithms. There we developed a new clustering algorithm which combines hierarchical clustering and k-means clustering.
I also worked with Prof. Dongsheng Che to predict Genomic Island in bacterial genomes. I am the developer of EGID - an ensemble algorithm to predict genomic islands in genomic sequences which performs 12.14% better than the prevoius best method.
I have authored several research papers in peer-reviewed Journals and Conference proceedings. List of projects is avalilable here and you can find a complete list of my papers in the publications page.